INOV8 R3ta Plus 1 is a next-generation hybrid injectable pen combining the powerful weight loss and metabolic control of Retatrutide with the mitochondrial support and performance enhancement of MOTS-c. Designed for both body composition and longevity, R3ta Plus 1 represents the cutting edge of metabolic medicine.
Each 2.6 mL Pen (240 clicks) contains:
- Retatrutide: 30 mg
- MOTS-c: 50 mg
Per Click (≈0.0108 mL):
- Retatrutide ~0.125 mg
- MOTS-c ~0.208 mg
Directions for Use
- Frequency: Twice weekly (approx. every 3–4 days).
- Best Time: Morning or early afternoon → maximizes appetite control, insulin sensitivity, and daytime energy.
- Method: Subcutaneous injection (rotate injection sites, sterile needles only).
- Storage: Refrigerate (2–8 °C), protect from light.
Suggested 12-Week Protocol:
| Weeks | Dose (Clicks) | Retatrutide | MOTS-c | Focus |
|---|---|---|---|---|
| 1–2 | 10 clicks | 1.25 mg | 2.08 mg | Gentle start, appetite reset |
| 3–4 | 14 clicks | 1.75 mg | 2.9 mg | Metabolic activation |
| 5–8 | 20 clicks | 2.5 mg | 4.2 mg | Weight loss acceleration, insulin support |
| 9–12 | 28 clicks | 3.5 mg | 5.8 mg | Peak effect: fat loss, mitochondrial energy |
Pen Longevity
| Clicks per Dose | Doses per Pen (240 clicks) | Weeks of Supply (2x Weekly) |
|---|---|---|
| 10 clicks | 24 doses | 12 weeks |
| 14 clicks | 17 doses | ~8½ weeks |
| 20 clicks | 12 doses | 6 weeks |
| 28 clicks | 8 doses | 4 weeks |
Compound Data
| Ingredient | Function | Benefits |
|---|---|---|
| Retatrutide | Triple-agonist (GLP-1, GIP, Glucagon receptors) | Potent appetite suppression, enhanced fat loss, improved glycemic control |
| MOTS-c | Mitochondrial peptide regulating AMPK pathway | Increases insulin sensitivity, enhances endurance, improves fat metabolism, supports cellular resilience |
Quality Assurance
- Produced in a GMP-certified sterile facility with rigorous quality control.
- Raw peptides validated by HPLC and MS testing for purity.
- Batch-coded pens with traceability and expiry date.
- Cold-chain shipping ensures MOTS-c and Retatrutide remain stable.
- Supplied with sterile, medical-grade needles.
Safety & Warnings
- Adult use only (18+).
- Not suitable during pregnancy, for individuals with active cancers, or severe liver/kidney impairment.
- Monitor: blood glucose, lipids, IGF-1, liver/kidney markers.
- Mild GI side effects possible in early weeks (common with GLP-1 agonists).
- Cycle in 12-week blocks with 2–4 week breaks before repeating or rotating therapies.
Additional Reading
- NEJM: Clinical trials of Retatrutide in obesity and diabetes management.
- Nature Metabolism: Role of MOTS-c in metabolic health and mitochondrial regulation.
- Cell Reports: AMPK activation and MOTS-c in skeletal muscle adaptation.
- Lancet Diabetes & Endocrinology: Combination incretin therapies and long-term weight loss.
R3ta Plus 1 is more than a weight loss tool — it’s a hybrid solution uniting metabolic control and cellular energy.
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Disclaimer
All INOV8 Pharma products are intended for laboratory and research purposes only. They are not approved for human consumption, medical use, or therapeutic application. These products are not intended to diagnose, treat, cure, or prevent any disease. Always handle peptides in accordance with proper laboratory safety and research protocols.




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